Scientific publications

October 2026
Characterizing micvotabart pelidotin’s (MICVO’s) anti-tumor, immunostimulatory, and synergistic activity in immunotherapy sensitive and refractory tumor models – Poster Number: 64
World ADC Poster
September 2026
Development of a Novel Immunohistochemistry Assay to Characterize Extradomain-B of Fibronectin (EDB+FN) Protein Expression in Solid Tumors (Laboratory Investigation, 2026; 106)
Article
April 2026
Mouse analog of micvotabart pelidotin, an antibody-drug conjugate targeting extradomain-B of fibronectin, demonstrates antitumor efficacy in an immunotherapy-refractory syngeneic head and neck squamous cell carcinoma model – Abstract Number: 4406
AACR Poster
January 2026
Detection of Anti-drug Antibodies (ADAs) to an Antibody-drug Conjugate (ADC) PYX-201 in Human Plasma Using a Novel Electrochemiluminescence (ECL) Immunoassay (Current Analytical Chemistry, 2026, 22, 347-360)
Article
November 2025
A Phase 1/2 Study of a First-in-Class Non-Cellular Antibody-Drug Conjugate, Micvotabart Pelidotin (MICVO), in Combination with Pembrolizumab in Select Advanced Solid Tumors – Abstract Number: 548
SITC Poster
October 2025
Micvotabart pelidotin induces immunogenic cell death markers and activates tumor immune cells in pre-clinical studies – Abstract Number: A112
AACR-NCI-EORTC Poster
October 2025
Micvotabart pelidotin, an ADC targeting non-cellular EDB+FN, induces an immune response in tumors from participants in a phase 1 dose escalation study – Abstract Number: A114
AACR-NCI-EORTC Poster
October 2025
Characterization of micvotabart pelidotin target binding properties and extracellular payload release – Abstract Number: A116
AACR-NCI-EORTC Poster
October 2025
Development of multiplex immunofluorescence workflows for characterizing tumor-immune and stromal compartments for pharmacodynamic assessments of solid tumors – Abstract Number: A117
AACR-NCI-EORTC Poster
October 2025
Mouse analog of micvotabart pelidotin sensitizes a refractory syngeneic breast cancer model to anti-PD1 therapy – Abstract Number: A115
AACR-NCI-EORTC Poster